CREATION OF DRUG COATINGS ON MEDICAL ARTERIAL 
STENTS USING THE ELECTROCHEMICAL METHOD

Tatyana A. Ermakova

Candidate of Sciences (Chemistry), Associate Professor, 
Department of Forensic Examination and Physical Materials Science, 
Volgograd State University
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Prosp. Universitetsky, 100, 400062 Volgograd, Russian Federation

Valeriy T. Fomichev

Doctor of Sciences (Engineering), Professor,
Department of Forensic Examination and Physical Materials Science, 
Volgograd State University
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Prosp. Universitetsky, 100, 400062 Volgograd, Russian Federation

Dmitriy V. Mordvinkin

Student, Department of Forensic Examination and Physical Materials Science, 
Volgograd State University
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Prosp. Universitetsky, 100, 400062 Volgograd, Russian Federation

Abstract. Using the adsorption properties of polyvinylpyrrolidone and the antitrombocytic properties 
of acetylsalicylic acid in operation, a drug coating was applied to a metal stent by an electrochemical 
method. Optimal conditions of electrochemical deposition of drug coatings on metal surfaces are selected. 
The obtained drug coating was evaluated and the thickness of the drug coating was calculated. 
Drug-coated stents are the most significant innovation in invasive cardiology of the early 21st century. 
In this regard, methods that allow the rapid, effective and long-term restoration of blood circulation 
in a damaged vessel are being actively developed. Stenting coronaries that nourish the heart is a 
sparing intravascular surgery with expansion of stenosed or occluded areas of the arteries by the stent. 
The mesh structure allows it to be delivered to the installation site in a compressed state, and in place – 
to expand to the size required by the vessel. Since the implant is a foreign body, the introduction of 
a stent provokes the activation of blood coagulation mechanisms, which is the cause of restenosis – 
repeated blockage of the vessel. To reduce the risk of restenosis, a drug coating is applied to the stent 
to prevent blood clots from forming in blood vessels.

Key words: electrolysis, precipitation, stent, polyvinylpyrrolidone, acetylsalicylic acid, drug coating.

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